Analysis Note

ControlHuman Brain Tissue

Application

Research CategoryNeuroscience

Research Sub CategoryDevelopmental Neuroscience

This Anti-Tbr2 Antibody is validated for use in IH for the detection of Tbr2.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Tbr2 (a T-domain transcription factor) is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Trb2 has been shown to play a role in the development of the neocortex and functions in the differentiation pathway of radial glia to postmitotic projection neuron.

Immunogen

Epitope: Internal Domain

KLH-conjugated linear peptide corresponding to mouse Tbr2.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Quality

Evaluated by Immunohistochemistry of human brain tissue.

Immunohistochemistry Analysis: A 1:300 dilution of Anti-Tbr2 antibody from a previous lot detected Tbr2 in mouse and human brain tissue.

Specificity

This antibody recognizes Tbr2.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.